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The Biden administration says it has a plan to curb fatal overdoses by 13% by 2025. But as more synthetic opioids reach the U.S., there's skepticism interdiction can slow the flow of deadly drugs.

U.S. Gen. Mark Milley says Ukraine faces a shortfall of weapons and troops while battling Russia's latest offensive.

The U.S. health system now produces debt on a mass scale, a new investigation shows. Patients face gut-wrenching sacrifices.

Shannon Hunt remembers mechanic Scott "Scooter" Stewart of Shiloh, Ill., whom she called her "bonus dad."

Illinois' family service agency is routinely keeping wards of the state in Chicago's juvenile jails beyond their sentences — because of a lack of where to put them.

The Justice Department announced multiple hate and firearms charges against the white man accused of killing 10 people at a Buffalo market in a predominantly Black neighborhood.

Intimidated by grilling? In this guide, learn the basics from which type of grill to choose, to how to maintain a fire and create different temperature zones, to tips on tools and safety.

The Federal Reserve raised interest rates by three-quarters of a percentage point Wednesday in an effort to combat stubbornly high inflation. It's the biggest rate increase in 28 years.

The federal complaint gives a new account of Payton Gendron's movements in the store. It also alleges that he said "Sorry" to at least one of his white victims.

In Tuesday's Republican primaries, Trump-backed candidates won up and down the ballot in Nevada, while he saw a split in South Carolina, where he endorsed challengers to two GOP incumbents.