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NPR's Ayesha Rascoe plays the puzzle with Weekend Edition puzzlemaster Will Shortz along with listener Cynthia Rose of Littleton, Colorado.

New recommendations for early treatment of hypertension to prevent strokes, heart attacks and dementia come as an experimental medication is shown to lower blood pressure in hard-to-treat patients.

Japan's Prime Minister Shigeru Ishiba has expressed his intention on Sunday to step down following growing calls from his party to take responsibility for a historic defeat in July's parliamentary election.

Russian president Vladimir Putin spent the week in China, attending a summit and very publicly aligning himself with Xi Jinping. Alexander Gabuev, director of the Carnegie Russia Eurasia Center, explains why this matters to the US and Ukraine.

Davey Johnson, an All-Star second baseman who won the World Series twice with the Baltimore Orioles as a player and managed the New York Mets to the title in 1986, died Friday.

Dryden backstopped the NHL's most successful franchise to championships in six of his eight seasons in the league from 1970-71 to '78-79. He died after a fight with cancer.

Dylan O'Brien and James Sweeney craft a kind of chemistry that is equal parts funny and heart-wrenching.

The congressional redistricting fights that President Trump sparked in Texas, California and other states have led some advocacy groups to reconsider their strategies against partisan gerrymandering.

In Zambia, we met people who are HIV positive, couldn't get drugs to suppress the virus after U.S. aid cuts and were seeing symptoms. We checked in on them — and the man who's been their champion.

Sinner is trying to become the first repeat men's champion in New York since Roger Federer won the tournament five years in a row. Alcaraz hasn't dropped a set as he pursues his second U.S. Open title.