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The state's largest wildfire on record is burning across large swaths of the Texas Panhandle. The fire has prompted evacuations and has already devastated scores of ranches, farms and small towns.

The agency is replacing its COVID-specific guidance with general guidance for respiratory viruses that says people should stay home when they are sick.

The CDC is dropping its isolation guidance for COVID, instead advising around respiratory viruses in general. The change reflects the reality that severe outcomes are less frequent, says the director.

As marijuana has gone mainstream in America, lawmakers in states that legalized it are now grappling with a new question: Should high-potency pot products be regulated differently?

Former President Trump is in Fort Pierce, Fla., for a key hearing in his criminal indictment on charges of withholding and hiding classified documents. The judge may postpone the trial's start.

Efforts to curb social media for minors are popping up in state legislatures. Advocates say it'd help temper harmful mental health effects. But the constitutionality of all out bans is up for debate.

NPR's Ari Shapiro talks with glaciologist Ted Scambos about the conclusion of a multi-year study of Antarctica's Thwaites Glacier, the "plug" holding back a formidable amount of ice.

Republican Sen. Mitch McConnell is an institution in Kentucky. He has been the Senate leader for his party since 2007. And state political leaders say his leadership has helped Kentucky.

Russian opposition leader Alexei Navalny was buried in Moscow Friday. Thousands of mourners were there along with a large police presence. The event remained peaceful.

NPR's Ari Shapiro speaks with John McWhorter, Columbia University linguist and New York Times columnist about the recent Merriam-Webster declaration that English sentences may end with prepositions.